I thinks it's too soon to tell if it is helping with Chessie's anal gland issues because they only occurred occasionally. But so far no anal gland issues since starting her on glandex. However I will mention that we've noticed great improvement in the quality of her stool - they appear to be more substansive and fiberous. I have to assume this is helping with the natural process of anal gland emptying. Also, she loves the stuff which is wonderful because she's always been a finicky eater. Now when we crumble some Glandex into her dry food she gobbles it all up. It's great to finally see her enjoying her meals. Finally, I love the fact that the product contains probiotics because I'm sure this will help her her entire digestive track healthy. Thank you to the Glandex folks!